The Leicester flanker, who was withdrawn after just 55 minutes of England's RBS Six Nations defeat to Ireland, is replaced at openside flanker by Worsley for the trip to Murrayfield.

Worsley, 32, returns to the starting XV for the first time since suffering knee ligament damage in the opening minute of England's 19-6 defeat to New Zealand in November.

England manager Martin Johnson has made just one other enforced change to the starting XV, with Louis Deacon replacing the injured Simon Shaw in the second row.

Northampton's versatile lock Courtney Lawes comes onto a reshuffled bench which features a return for hooker Steve Thompson and a first call-up for the uncapped Leicester scrum-half Ben Youngs.

The 20-year-old has replaced Paul Hodgson, who he played against on Saturday in Leicester's 35-19 Guinness Premiership victory over London Irish.

Youngs' father, Nick, won six caps for England at scrum-half between 1983 and 1984.

Scotland, coached by the former England boss Andy Robinson, return to Murrayfield on the back of a defeat to Italy in Rome and chasing their first victory of the tournament.

But England have lost on each of their last two visits to Murrayfield and Saturday's game marks the 20-year anniversary of Scotland's 13-7 Grand Slam-clinching victory.

Leeds-born Danny Care continues at scrum-half.

There is no place in the 22 for Leeds's South Africa-born flanker Hendre Fourie who was called into the squad for the first time yesterday.

Nor is there a place for Otley-born Mike Tindall, or former Leeds player Tom Palmer - who were both added to the squad as cover yesterday.

The trio will stay with the squad in case of injury to the players ahead of them.

England: D Armitage (London Irish); M Cueto (Sale), M Tait (Sale), R Flutey (Brive), U Monye (Harlequins); J Wilkinson (Toulon), D Care (Harlequins); T Payne (Wasps), D Hartley (Northampton), D Cole (Leicester); L Deacon (Leicester), S Borthwick (Saracens, captain); J Haskell (Stade Francais), J Worsley (Wasps), N Easter (Harlequins). Replacements: S Thompson (Brive), D Wilson (Bath), C Lawes (Northampton), L Moody (Leicester), B Youngs (Leicester), T Flood (Leicester), B Foden (Northampton).

Scotland: H Southwell (Stade Francais); S Lamont (Scarlets), N De Luca (Edinburgh), G Morrison (Glasgow), M Evans (Glasgow); D Parks (Glasgow), C Cusiter (Glasgow, captain); A Jacobsen (Edinburgh), R Ford (Edinburgh), E Murray (Northampton); J Hamilton (Edinburgh), A Kellock (Glasgow); K Brown (Glasgow), J Barclay (Glasgow), J Beattie (Glasgow). Replacements: S Lawson (Gloucester), G Cross (Edinburgh), N Hines (Leinster), A MacDonald (Edinburgh), R Lawson (Gloucester), P Godman (Edinburgh), S Danielli (Ulster).