Sheffield Wednesday progressed to the fifth round of the FA Cup for the first time in over a decade after coming from behind to beat Hereford United 4-1 at Hillsborough.
The Owls could be joined in Sunday's draw by Yorkshire neighbours Huddersfield Town, but they face a might challenge in beating Arsenal at the Emirates Stadium.
In the Championship, Hull City held leaders QPR to a goalless draw at the KC Stadium, while in League Two, there was a welcome return to winning ways for Rotherham United who thrashed Stockport County 4-0.
Bradford City were denied a much-needed win, when leaders Chesterfield equalised in stoppage time for a 2-2 draw.
York City crashed to a 4-0 defeat at Southport after playing with 10 men for 88 minutes when David McGurk was sent off in the opening exchanges.
FA Cup fourth round
Arsenal v Huddersfield Town (Sunday, 12)
Team news: Lee Clark is without both top scorer Jordan Rhodes (ankle) and Benik Afobe (ineligible) for the trip to Arsenal so Lee Novak could start up front alongside Alan Lee. Also out for the Terriers are Alex Smithies (knee), Liam Ridehalgh (glandular fever) and Damien Johnson (knee), while the Cup tie has also come too soon for Gary Naysmith following his return to training.
FT Sheffield Wednesday 4 Hereford United 1
Stuart Fleetwood (8) puts hosts ahead before Darren Potter (15) equalised. Clinton Morrison converted a second-half penalty as Joe Heath was red carded for the visitors who played the last 20 minutes with 10 men. Wednesday added further goals from Jermaine Johnson and Morrison.
FT Hull City 0 QPR 0
Neither side could break the deadlock in a goalless match.
FT Chesterfield 2 Bradford City 2
Danny Whitaker put hosts ahead before David Syers (12) equalised for City and James Hanson (53) made it 2-1. Jordan Bowery grabbed a stoppage-time equaliser.
FT Rotherham United 4 Stockport 0
An Aaron Brown own goal after 12 minutes give Millers the lead, before Ryan Taylor (21, 57) increased their advantage. Adam Le Fondre (34) added a third.
Blue Square Premier
FT Southport 4 York City 0
David McGurk shown red card after two minutes before goals from Chris Lever (3) and Shaun Whalley (4) put hosts ahead. Kevin Lee (21) added a third before Whalley made it 4-0.
The FA Cup
Aston Villa 3-1 Blackburn
Birmingham 3-2 Coventry
Bolton 0-0 Wigan
Burnley 3-1 Burton Albion
Everton 1-1 Chelsea
Sheff Wed 4-1 Hereford
Southampton 1-2 Man Utd
Stevenage 1-2 Reading
Swansea 1-2 Leyton Orient
Torquay 0-1 Crawley Town
Watford 0-1 Brighton
Crystal Palace 0-0 Norwich
Hull 0-0 QPR
Npower League One
Brentford 1-2 Yeovil
Carlisle 2-2 Oldham
Plymouth 1-2 Bournemouth
Swindon 0-0 Exeter
Walsall 6-1 Bristol Rovers
Npower League Two
Barnet 0-2 Southend
Chesterfield 2-2 Bradford
Gillingham 2-1 Aldershot
Lincoln City 1-0 Port Vale
Oxford Utd 1-1 Cheltenham
Rotherham 4-0 Stockport
Blue Square Premier
Bath City 4-0 Cambridge Utd
Eastbourne Boro 2-3 Grimsby
Fleetwood Town 2-0 Forest Green
Hayes & Yeading 0-4 Kidderminster
Histon 0-0 Newport County
Mansfield 2-3 Wrexham
Rushden & D'mnds 1-1 Tamworth
Southport 4-0 York
Blue Square North
Blyth Spartans 3-2 Stafford Rangers
Corby 1-6 Eastwood Town
Hinckley Utd 3-1 Gainsborough
Nuneaton 1-1 Redditch
Solihull Moors 2-2 Harrogate Town
Vauxhall Motors 2-1 Gloucester
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