Highways England Yorkshire warned drivers of "severe delays" on the approach to the accident on the westbound carriageway.
Emergency services are at the scene.
The agency added: "Just under 8 miles of slow moving traffic is approaching the scene, so allow plenty of extra time for your journey this morning."
The AA said the accident involved a car and a van on the M62 affecting J23 A640 New Hey Road (Huddersfield) to J22 A672 (Rishworth Moor).
Congestion is back to J24 (Ainley Top).