Damien Webb, 32, was reported missing by his family on Christmas Day and police are concerned because, they say, it is not like him to go missing.
He lives in Park Grove, Macclesfield but it is thought he may have travelled to Leeds.
Inspector Steve Griffiths said: “This behaviour is out of character and we are concerned for his welfare. We are appealing to anyone who may have seen Damien to come forward.”
He urged Mr Webb himself to contact police.