Police discovered three cannabis farms at two properties on Benjamin Street and one on Bourne Avenue during Wednesday’s raids.
Around 200 plants and growing equipment were seized by officers.
Two men, aged 26 and 25, were arrested on suspicion of production of a controlled Class B drug with intent to supply. Both men have been released on bail.
Insp Mark Chamberlain, of Wakefield Police, said: “Police seized a large amount of cannabis plants and growing equipment.
“The plants have now been sent for forensics. We would urge the community to contact us if they have any suspicions of drugs being grown in their area.”
Anyone with information should call Wakefield Police on 101 or Crimestoppers, anonymously, on 0800 555 111.