The burglary happened in Harrogate Road, sometime between 9am and 6pm yesterday (Monday).
A number of rare coins were stolen from the property, including a 007 James Bond 10p coin.
North Yorkshire Police has today appealed for witnesses to come forward.
Anyone with information is asked to contact police on 101.
More in crime: Man arrested on suspicion of murder after death crash in Sheffield
More in crime: Police searching for flasher with baggy green trousers who exposed himself in Leeds
More in crime: Harrogate police issue CCTV appeal after burglary at KFC in Starbeck