Three men have been arrested on suspicion of assault after a disturbance at a property in Beverley during the early hours.
Humberside Police said emergency services had attended a disturbance in Flemingate shortly before 3.15am today.
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It resulted in a 49-year-old man being taken to hospital for treatment to serious injuries.
Anyone with information is asked to call police on 101, quoting log 42 of 13/09/18.
Information can also be passed on anonymously via the independent charity Crimestoppers on 0800 555 111.