Darren Grundy, from Birdwell in Barnsley, was arrested during the height of the 2020 coronavirus lockdown, after information was passed by the NCA to Greater Manchester Police.
Officers intercepted the van he was driving on 21 April 2020 on the A56 Chester Road in Manchester.
They found blocks containing approximately two kilos of cocaine and £150,000 in cash hidden in a void in the floor of the vehicle.
The drugs would have had a street value of almost £160,000 if cut and sold on the streets.
The investigation into Grundy was linked to Operation Venetic, the UK law enforcement takedown of the encrypted communications platform Encrochat.
NCA investigators later charged Grundy with possessing class A drugs with intent to supply and money laundering offences.
At Sheffield Crown Court on Wednesday November 3 he pleaded guilty, and was sentenced to two years and eight months in prison on Thursday December 2.
A confiscation hearing will be held in May 2022 for the £150,000 in cash and his house in Barnsley.
NCA branch commander Martin Clarke said: “Organised crime groups rely on people like Grundy to move their product and money around. He was obviously trusted by his criminal contacts to do this with large amounts of both cash and drugs.
“Fortunately, though swift working with our colleagues at Greater Manchester Police, we were able to seize both, and prevent profits being re-invested in further criminality.”