New joints may be grown from patients' own cells

A team of scientists has, for the first time, shown it is possible to grow joints inside the body which have a full range of movement and can bear weight.

The joints could potentially last longer than commonly-used artificial joints, saving elderly patients from having to undergo gruelling operations to replace those that have worn away.

The study was carried out on rabbits but researchers believe it paves the way for a future where people grow their own bone and cartilage.

Prof Jeremy Mao and his team at Columbia University Medical Centre in New York led the study with colleagues at the University of Missouri and Clemson University in South Carolina.

They used a computer to help create artificial scaffolds that were anatomically the same size and shape as rabbit hip joints. The scaffolds were infused with a growth factor and implanted into 10

rabbits after their own hip joints had been removed.

Attracted by the growth factor, their own stem cells went to the location of the missing joint and regenerated cartilage and bone in two separate layers.

Just three to four weeks after surgery, the rabbits had regained movement and could bear weight similar to animals who had never undergone surgery.

The rabbits had grown their own joints using their own stem cells, instead of relying on an injection of stem cells into their body.The study was published online in The Lancet medical journal.