The places in the city centre running event are likely to be snapped up following a strong uptake last year which saw runners raise more than 44,000 on behalf of Yorkshire Cancer Research, which has its headquarters in Harrogate.
The Jane Tomlinson Run for All Leeds 10k race on Sunday, June 19 next year, is open to all abilities and participants can choose to run, walk or wheel it through Leeds city centre along with tens of thousands of others.
Money raised by those running in aid of Yorkshire Cancer Research will fund world-class cancer research, diagnosis and treatment at Yorkshire's five universities and associated teaching hospitals in Leeds, Bradford, Hull, Sheffield and York.
Jane Tomlinson was an inspiration to many. Having been diagnosed with terminal cancer in 2000, the mother-of-three went on to raise nearly 2m for children's and cancer charities before she passed away in September 2007.
The Run For All flagship event, the Leeds 10K, was set up in 2007 as a legacy to her fundraising achievements.
Yorkshire Cancer Research is an official partner for the next Leeds 10K which in 2011 will celebrate its fifth anniversary.
Log onto www.yorkshirecancerresearch.org.uk to apply for a place in aid of Yorkshire Cancer Research online or call the charity's fundraising team on 01423 877210 to register over the phone.
All participants will receive a special fundraising pack which includes a Yorkshire Cancer Research T-shirt and tips on training. Minimum age for entries is 15.
The charity has been funding research into cancer in all its forms for the last 85 years and supporting research teams across Yorkshire in their goal to find the causes and cures for cancer.