The 75-year-old New Yorker, famous for his roles in The Godfather, Taxi Driver and Goodfellas, is appearing at two exclusive black tie dinner evenings in Leeds and Birmingham this November.
See inside the hotel where Arnold Schwarzenegger stayed in YorkshireAn Experience with Robert de Niro at the New Dock exhibition centre in the Royal Armouries will take place on November 26 - and fans have already signed up in large numbers ahead of tickets going on sale.
The event isn't cheap - tickets start from £145, including a meal, and go up to £365.
It's the first time the veteran actor, director and producer has shared his life story with a live audience.
Tickets go on sale on Wednesday October 3 at 10am.
In 2017 actor and Mr Universe winner Arnold Schwarzenegger appeared at a similar black tie evening at the Royal Armouries. He stayed at the Dakota Deluxe Hotel before heading to local gym 1RM Elite Training Studio for a workout.