Part of Stonegate Road has been closed through the night since the crash at 9.45pm on Saturday, and police are still on scene with a cordon in place today (Sunday).
A boy aged 12 was among five people killed after a stolen car crashed into a tree.
Police said two 15-year-old boys also died along with two men aged 24 and 28.
Police were called to reports of a crash on Stonegate Road in Meanwood just before 10pm last night. (Saturday Nov 25)
West Yorkshire Police have confirmed a stolen Renault Clio collided with a tree. Two 15-year-old boys were arrested and are currently in police custody.
A West Yorkshire Police spokesman said family of all the deceased have been informed.
The spokesman added: "The road remains closed and West Yorkshire Police major collision enquiry team are conducting an investigation into the exact cause of the collision." Call West Yorkshire Police with information on 101