The family of six-year-old cancer sufferer Bradley Lowery have confirmed he has died.
The County Durham youngster's condition had deteriorated significantly in the past few days, and his parents had already announced he had become unresponsive.
He passed away at home at 1.35pm on Friday.
A message posted on Facebook page Bradley's Fight read:
"My brave boy went with the angels today 07/07/17 at 13:35, in Mammy and Daddy's arms surrounded by his family.
"He was our little superhero and put the biggest fight up but he was needed elsewhere. There are no words to describe how heartbroken we are. Thank you everyone for all your support and kind words.
"Sleep tight baby boy and fly high with them angels."
Bradley, his parents and elder brother recently enjoyed a final holiday together on the Yorkshire coast, where they were welcomed by visitor attractions such as Scarborough Sea Life Centre.
The Sunderland fan has also been a mascot at several of the club's matches, as well as England games.
The club posted an official statement paying tribute to Bradley:
"Our thoughts and prayers are with Bradley’s parents, Gemma and Carl, his brother Kieran and their family and friends. We extend our love and support to them, now and always.
"Bradley captured the hearts and minds of everyone at our club with his indomitable spirit, tremendous courage and beautiful smile, which could light up even the darkest of rooms. Despite battling neuroblastoma for much of his all too short life, he demonstrated a bravery and fortitude beyond his years that humbled us all. He was truly an inspiration.
"His heart-warming friendship with players and staff alike epitomised the impact this wonderful little boy had on everyone he met. He had a special relationship with Jermain Defoe and their feelings for each other were evident for all to see. Jermain, naturally, is heartbroken.
"Bradley’s story not only touched our club and our fans, but also the wider football community. Football can be a powerful force for good and our sport came together to embrace Bradley’s fight in a unique way. We would like to extend our sincere thanks to every club and fan who supported Bradley in recent months and showed such warmth and kindness to the Lowery’s - we are truly grateful.
"Throughout his illness, Bradley’s family and friends have worked tirelessly to increase awareness of this brutal disease. Their fundraising campaign, initially for Bradley’s treatment and subsequently to raise money for the foundation that will bear his name, will ensure that other youngsters and parents facing the devastation of life-threatening illnesses will have the help and support they so desperately need.
"Bradley’s passing will have a profound effect on everyone and we understand that people will want to reach out to support the Lowery’s. We would kindly ask on their behalf however, that that they are given the privacy they need as a family at this most unimaginably difficult time. We will continue to support them in whatever way we can."