Sundara Karma, Metronomy and Tom Grennan will top the bill during the event on Saturday, May 4, 2019.
Swim Deep, Dream Wife, Black Honey and Sports Team are also due to take the stage when the event returns.
Live at Leeds is a part of Leeds International Festival 2019, an “annual celebration of new ideas, local creativity and international culture” taking place between May 2 and 12.
Live At Leeds 2019 festival director Andy Smith said: “It’s really good to see breakthrough artists coming back for 2019, both Sundara Karma and Tom Grennan cut their teeth at the event making their first appearances in 2016 and ‘17 respectively.
“They’ve both had a great few years, selling out Leeds Academy and enjoying critical acclaim since their last LAL appearances; it’s amazing to welcome them back topping the bill.”
Tickets are on sale from Â£36 plus booking fee at https://www.liveatleeds.com