The Royal Mint has released a proof set in honour of the “revolutionary” seven-sided coin, which was first introduced in 1969.
It said the designs had been carefully selected to celebrate key cultural milestones and favourite pieces of coin collectors.
The Kew Gardens coin is a collector’s item because of its low mintage of just 210,000 – making it the rarest 50p design in circulation.
Visitors to The Royal Mint Experience in Wales will also be able to strike their own 2019-dated 50p Britannia New Pence.
The commemorative 50p set will be available to purchase from www.royalmint.com in a range of finishes, with prices starting from £90.