Crews from across West Yorkshire were drafted in to help tackle the fire at Cliff House, the site of the former all boys school in Fawcett Lane.
The initial call was received at 8.40pm and the first firefighters on site issued a priority assistance message for a eight further appliances to be dispatched.
It took around three hours to bring the fire at the derelict building under control.
Firefighters used breathing apparatus, hose reels, combined aerial platforms and ground monitors during the response.
A West Yorkshire Fire Service spokesman said this morning that one fire engine and an aerial platform had remained there throughout the night.
An aerial platform will remain on site from 8am to monitor the situation until a fire officer visits the site to see if the incident can be closed.
The cause of the fire is yet to be established.