Police are seeking witnesses and dash cam footage after a crash near York left four people in need of hospital treatment.
A call was received by police just after 4pm on Wednesday reporting that two cars had collided on the A59 between Poppleton and Hessay.
The collision involved a grey Nissan Note, which was travelling towards Harrogate, and a black Vauxhall Astra travelling in the opposite direction.
North Yorkshire Police said a woman in her 70s, who was a passenger in the Nissan, was taken by air ambulance to hospital for treatment.
Her injuries are believed to be serious but not life-threatening.
The driver of the Nissan, a man in his 70s, and the driver and a passenger of the Vauxhall, who are both in their 60s, were taken by road ambulance to hospital for treatment.
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Road closures were put in place while the initial collision investigation was carried out and the vehicles involved were recovered.
The road was reopened at around 8.50pm on Wednesday.
Anyone who witnessed the collision or the events surrounding it is urged to contact North Yorkshire Police on 101, quoting reference 12180195272.