Warrington has been taken the distance in two previous challenging title defences in his home town.
Warrington won every round against tough Australian Joel Brunker in September. In April he brilliantly handled a significant height disadvantage against six-foot Japanese Hisashi Amagasa to record another wide decision win.
The 25-year-old next faces Irish fans’ favourite Hyland, who is back in action having challenged WBC king Gary Russell Jr for the world title.
“Amagasa and Brunker were tough nights, but we got the wins,” said Warrington.
“I had to box clever in the last few fights, but I think this one will be toe-to-toe. Patrick doesn’t take a backwards step in his fights and I think that I’ll be able to show that I can really dig.”
Warrington’s clash with Hyland tops a huge card to be shown live on Sky when Luke Campbell faces former World champion Argenis Mendez.
Huddersfield’s Tyrone Nurse will defend his British Super Lightweight title against Hull’s Tommy Coyle, and Barnsley’s Josh Wale gets a shot at the Commonwealth Super-Bantamweight title against Birmingham’s Gamal Yafai.