The Red Devils have appointed Ralf Rangnick to replace Ole Gunnar Solskjær with the German set to take charge of the side for the first time this weekend.
Now the club are reportedly seeking to bring Struber in as assistant after he and Rangnick worked together at Red Bull Salzburg.
Struber is well known in these parts, having masterminded Barnsley's stunning escape from Championship relegation in 2019-20.
The Austrian left the Tykes last autumn to take on the role of head coach at New York Red Bulls.
Barnsley were seven points from safety when Struber arrived at Oakwell in November 2019. The Tykes then picked up six points in their final two games of the 2019-20 season, scoring winning goals in injury time against Nottingham Forest and Brentford to secure survival.
He left the club last autumn for New York Red Bulls with the club in the Championship relegation places.