Anderson was dismissed for two bookable offences in Tuesday night's seven-goal routing of Chorley in an FA Cup first-round replay - representing the only downside to a wholly positive night.
Manager Grant McCann, who was unhappy with the two yellow cards issued by referee Darren Drysdale, has just one recognised senior centre-back at his disposal for the weekend in the shape of Andy Butler, with Joe Wright sidelined with injury.
Options to feature at the weekend include recent short-term signing Shaun Cummings, whose last taste of league action arrived in mid-March or switching Niall Mason to the centre and moving Matty Blair from midfield to right-back.
Speaking after Tuesday night's game with Chorley, McCann said: "If Tom is going to be suspended, then we will probably be looking at Shaun or Matty Blair in that position really. Those are probably our two options."