The Tigers slumped to a shock 4-1 reverse at Elland Road in midweek courtesy of a below-par performance against their rivals from West Yorkshire.
Pearson has warned his players there must be no repeat today when Crystal Palace come to the KC Stadium.
The Tigers manager said: “We have put Tuesday’s game to bed. It was a strange performance and result, and what hindered us really was conceding either side of half-time.
“But we will put that behind us and look forward to what will be another tough home game.
“It is important that we have a positive performance and that we start winning at home. We need a reaction like Leeds had on Tuesday, we need to be positive and get the crowd behind us.
“Palace come here having had a decent start and I am sure they will play counter-attacking football, which we will have to deal with.
“More importantly, we have to perform to our maximum and that is what we will be looking for.”
Meanwhile, Ipswich Town manager Paul Jewell has confirmed his interest in Jimmy Bullard following the termination this week of his Tigers contract.
The 32-year-old, who spent time on loan at Portman Road last season, had two years remaining on his £48,000 per week deal and he could appeal against the decision.
Jewell said: “I spoke to Jimmy (on Thursday). I have spoken to him right the way through the summer. I think he was close to joining QPR earlier in the summer and he has told me that a couple of Premier League clubs were speaking to his representative.
“I have told him to keep us informed because we want to be at the front of the queue if possible.
“There will be other teams in for him, though, and I am sure he would prefer to go to a Premier League club – as any player would.
“He really enjoyed himself here last season, the players like him, the fans love him, so if we can afford him it is something we would be very, very interested in doing.”
Bullard, who joined City from Fulham for £5m, was suspended by the club following an incident on the pre-season trip to Slovenia.