The charity has been formed by Bantams legend Stephen Darby, who was diagnosed with motor neurone disease in 2018, alongside close friend Chris Rimmer - who was himself diagnosed with the condition five years ago.
The fixture will evoke memories of Liverpool's famous visit to Valley Parade in May 2000 when a goal from David Wetherall famously sealed City's Premier League survival.
Speaking of the occasion later this season, Darby said: “I am extremely grateful City and Liverpool will be playing each other during pre-season in support of the Darby Rimmer MND Foundation.
“They are two amazing clubs, who formed a massive part of my career. Both will always hold a special place in my heart.
“I cannot thank both clubs and sets of fans enough for their support.”