The marquee fixture sees Huddersfield Town welcome Hull City, while other stand-outs see Leeds United head to Burnley and Barnsley welcome Chesterfield - and there’s plenty more besides to set the pulses racing.
Here are five weekend pointers.
1: Burnley v Leeds United. Can the Whites flaky defence cope on the road at an automatic promotion contender?
The case for United’s defence has not been an overwhelming one for large tracts of this season, with two of the most pitiful capitulations coming at high-fliers Brighton and Middlesbrough, when the back four were all over the shop.
After some trails and tribulations in the past week, more especially for Giuseppe Bellusci, Leeds probably needed a weekend trip to Turf Moor like a hole in the head.
One thing is for sure, the likes of Andre Gray and ex-loanee Sam Vokes will be licking their lips ahead of Leeds’s arrival.
Can Leeds somehow man up for once at the back and take collective responsibility in front of a TV audience?
A rewind to the gutsy home showing in front of the cameras against Boro wouldn’t go amiss.
2: Huddersfield Town v Hull City. Points to prove for both White Rose combatants.
On paper at least, Hull’s need ahead of the game looks more pressing, with City - as Michael Dawson acknowledged - effectively needing to win their remaining seven matches to give themselves the best possible chance of getting automatic promotion.
At the end of February, all was set fair with Hull at the summit. But a run of one win in seven and seven points from the last 21 have blown them badly off course, with Steve Bruce and his players still smarting from a horror 4-0 loss at Derby last time out.
After the pre-Easter derby highs at Elland Road, successive defeats to Sheffield Wednesday and Boro ensure that Town are looking over their shoulders again a little - although despite a 3-0 midweek loss at the Riverside, results elsewhere mitigated the damage.
But just to be safe, Town need a win - or perhaps two - to start planning for next season, the sooner the better. A big game for them, too.
3: MK Dons v Rotherham United. Can the Millers avoid the dreaded manager of the month curse?
There should have been a steward’s enquiry had wily managerial veteran Neil Warnock not picked up the monthly gong following a magnificent March, with the Millers’ form in April not bad either.
A seven-match unbeaten run and 17 points from the last 21 is not just promotion form this Spring, but title form ahead of tomorrow’s clash at the side just below them in MK Dons, who occupy the final relegation spot and are six points in arrears.
For all the Millers’ outstanding form, they can’t relax yet and tomorrow is a real ‘biggie’.
Claim another head-turning victory and Warnock, who received his monthly award yesterday and the Millers, who will be backed by a big following in Buckinghamshire, can start celebrating.
4: Barnsley v Chesterfield. The ex-factor cometh.
Silverware is arriving with frequency at Oakwell.
With the JPT trophy safely in the cabinet after a super Sunday at Wembley, Paul Heckingbottom has now pocketed the manager of the month accolade for March after only two months at the helm of his boyhood club.
A fair old achievement, following on from Lee Johnson and Sam Winnall picking up the managerial and player gongs in January.
A more grounded guy you could not wish to meet than Heckingbottom, who in the aftermath of Wembley, quickly turned his attentions to ‘seven cup finals’ as the Reds aim to double by reaching the League One play-off showpiece at the home of football.
There’s work to do, starting with the arrival of the Spireites, with the game heightened by Danny Wilson’s first return to Oakwell since his sacking in February 2015.
It’s the start of a run of three games out of four on home soil for the Reds - opportunity knocks.
5: Bury v Doncaster Rovers. A must-win game for Rovers - lose and the consequences don’t need to be spelt out.
Fifteen games without a league win, four points from a possible 45, the statistics are almost tattooed in the minds of Rovers supporters.
Only victory will do at Gigg Lane for Rovers after those desperate late events down the road at Spotland last weekend.
Last-chance saloon time, really.