Winger Aaron Murphy scored a hat-trick of tries as Huddersfield halted their four-match losing run in emphatic fashion to put a dampener on Iestyn Harris’s first home match in charge.
The only disappointment for the Giants was the loss of hooker Shaun Lunt with a knee injury 11 minutes from the end.
Huddersfield looked a rejuvenated side from the kick-off and made a dream start with three tries in the first 12 minutes, all converted by Danny Brough.
Lunt forced his way over from dummy half for the opener, while the second came from deep, with centre Joe Wardle breaking from his own half to get Murphy over for his first try. Lunt then re-gathered his own kick over the Red Devils defence and the supporting Scott Grix kicked ahead for Brough to touch down.
Harris’s men finally got on the scoreboard on 25 minutes when left winger Francis Meli collected a long pass from Rangi Chase.
They added a second try to get back into the game when Adrian Morley proved unstoppable from 20 metres out to score his first try for his home-town club.
Jake Mullaney’s first conversion of the match cut the Giants’ lead to just eight points but Murphy scored his second try six minutes before the break.
A touch of magic early in the second half from Chase kept Salford in the hunt as he picked up a loose ball and conjured a try from nothing for Meli.
A powerful burst from substitute forward Ukuma Ta’ai then set up Leroy Cudjoe to get winger Jermaine McGillvary over the line. Brough kicked his fourth goal from the touchline and was also on target six minutes later after substitute Chris Bailey’s try.
Salford substitute Matty Ashurst pulled a try back on the hour, but Brough put over a penalty and then converted Murphy’s hat-trick try.
The Red Devils finished a well-beaten side but they had the final say when Meli completed his hat-trick.
Salford Red Devils: Mullaney, Johnson, Gleeson, Sa’u, Meli, Chase, Smith, Morley, Lee, Tasi, Hansen, Hock, Puletua. Substitutes: Ashurst, Griffin, Tomkins, McPherson.
Huddersfield Giants: Grix, McGillvary, Cudjoe, Wardle, Murphy, Brough, Wood, Crabtree, Lunt, Kopczak, Chan, Patrick, Lawrence. Substitutes: Bailey, Ta’ai, Mullally, Johnson.
Referee: T Roby (RFL)