Holders Leeds will be away to Hull in the quarter-finals of the Ladbrokes Challenge Cup.
The last-eight tie is a repeat of the 2005 final at the Millennium Stadium in which the Rhinos suffered a shock 25-24 defeat.
Leeds, who overcame Huddersfield 48-16 in the sixth round on Saturday, will be hoping for a repeat of their last trip to the KC Stadium in March when they won 43-12 after trailing 12-0 at half-time.
Leigh’s reward for knocking out Wakefield is a trip to 2012 winners Warrington, while St Helens will host Widnes and Catalans Dragons will go to Hull KR after beating Featherstone in the late match on Sunday.
The Centurions, who are enjoying a 25-match winning run going back to last July, have already claimed two Super League scalps and coach Paul Rowley says his Championship side will relish their trip to the Halliwell Jones Stadium.
“We’ve got to do it tough,” said Rowley. “We’ve done London and we’ve beaten Salford and Wakefield and now they’re thinking they’re not jumping just high enough yet so we’ll make them jump higher and send them to Warrington.
“At least it’s less petrol money for the fans.
“It’s a really tough challenge. Warrington are a good side with a wonderful coach. It will be interesting to see what the bookies give us that week.
“We’ll make it interesting as well. We’ll have a go.”
The tie promises a fascinating side show with veteran Mick Higham rumoured to be on his way from Warrington to Leigh.
Warrington last week rejected a bid for the former Wigan and St Helens hooker but left him out of the side that won at Dewsbury on Friday night.
“I’m pretty confident Micky Higham will play in that fixture,” Rowley said. “He’s a Warrington player so we’ll say it will be for Warrington but you never know, do you?”
Ladbrokes Challenge Cup quarter-finals draw: Hull KR v Catalans Dragons, Warrington v Leigh, Hull v Leeds, St Helens v Widnes. The quarter-finals will be played over the weekend of 27/28 June.