With 10 players making their senior debuts - and none of the side involved at Bradford on Sunday on duty - Fax, playing at Cougar Park because of ongoing pitch renovations at the Shay, were out of the contest by the end of the first quarter, with a full-strength Eagles side leading 20-0.
Jason Crookes, Patrick Burns, Anthony Thackeray and Josh Guzdek grabbed the early tries, with Pat Walker adding two conversions.
Fax responded with a Calvin Barber try, created by a slick pass from half back Fraser Stroud - who showed enough skill with very limited possession to hint at his talent - but Ben White’s conversion drifted wide.
The Eagles touched down twice more before half time, Ben Blackmore and Lewis Taylor going over, to push the score out to 30-4.
The ‘home’ side were much improved after the break, with the Eagles unable to add to their tally until the 59th minute, when Aaron Brown scored, Walker converting.
Fax grabbed a second through a kick and chase score from Reece Chapman-Smith to cut the gap to 36-8, but Ryan Millar, Blackmore and Crookes all went over in the closing stages to complete a relatively easy evening’s work for Mark Aston’s side.
Bradford also apid the price for their Challenge Cup exertions, losing 50-6 at Barrow Riaders.
And Featherstone Rovers failed to join Sheffield in Friday’s quarter-final draw, losing 22-16 at Widnes Vikings.