Sky Bet: United backed to have enough in reserve to see off battling Leeds

Leeds's aim is to get back to playing at venues such as that of the Premier League champions' on a regular basis but this is a fascinating test of their development under Simon Grayson.

It seems certain that Sir Alex Ferguson will utilise his squad players but the Red Devils should still have enough to win, although Leeds will certainly put up a fight.

A narrow home win looks a strong possibility and I would be tempted to cover 1-0 and 2-0 for Manchester United.

Both Sheffield clubs have home games against fellow Championship teams, with Wednesday looking for their first win in 12 as Crystal Palace visit Hillsborough. Former Blades boss Neil Warnock has got Palace moving in the right direction on a tight budget and they have lost only two of the last 12, with Victor Moses hitting form with five goals in the last seven. He will fancy his chances against Wednesday's vulnerable defence.

QPR are dangerous opponents for United and the Londoners are back on an even keel after the meltdown which led to Jim Magilton's departure.

These teams drew at Loftus Road a couple of weeks ago and another stalemate looks distinctly possible.

Hull manager Phil Brown may opt to rest a number of his players at Wigan and that could add up to a short stint in the FA Cup for the Tigers. Huddersfield, meanwhile, have a great chance of progressing if West Brom make numerous team changes for their match at the Galpharm Stadium.

Town's home record is outstanding – won 11 and drawn three in all competitions – and this game looks ripe for an upset of sorts.

Doncaster's opponents Brentford are in a decent run of form but there are seldom many goals in the West London club's games so look to back Under 2.5 Goals here.

Their last eight games have produced just eight goals and backing Doncaster to win 1-0 could be profitable.

It is a big day out for York, who face Premier League opposition in Stoke having won 10 of their last 11 games with Richard Brodie scoring goals galore. Stoke boss Tony Pulis will almost certainly select his reserves, but that should still be sufficient for the Potters to win through.

In League Two, Rotherham face a tough trip to leaders Rochdale, who are threatening to break clear at the top after a run of seven wins in eight games.

Bradford suffered a 3-1 home defeat to Shrewsbury on Saturday and will need to be wary of Cheltenham, who were impressive 2-0 winners at Dagenham.

Best bets

n Manchester United to beat Leeds 2-0.

n Sheffield Wednesday v Crystal Palace: Victor Moses to score.

n Sheffield United to draw with QPR.

n Wigan to beat Hull City.

n Huddersfield Town to beat West Brom.

n Brentford v Doncaster – Under 2.5 Goals.

n Stoke to beat York City.