In a poignant display the city's civic hall, town hall, museum, arena and the University of Leeds Parkinson building are among those included in the weekend tribute.
The moving two-day spectacle marked one year since medics were called to a hotel in York to what became the first confirmed case of Covid-19 in the UK.
Buildings have been illuminated in blue, in tribute to selfless NHS staff, working in hospitals and care settings, and yellow to symbolise grief awareness.
Coun Judith Blake, Leeds City Council leader, said: "The profound sadness of losing so many lives cannot be overstated and commemorating that loss and expressing our solidarity with those who have said goodbye to friends, loved ones and family members will be a poignant moment."
The tribute also recognises the "enduring courage and spirit in these toughest of times" of NHS and care staff, Coun Blake added.
Looking to the future Coun Eileen Taylor, the city's lord mayor, added: “We should also look ahead with a sense of hope and optimism that better days are on the horizon.”
The tribute comes as almost 80,000 people in Leeds have now received their first dose of the Covid vaccine, with vaccination sites up and running at venues around the city, the council said.
Everyone in Leeds is being asked to continue to do their bit to help fight the spread of coronavirus by:
- Staying home as much as you can and minimising contact with others when you do need to go out. Acting as though you have the virus is the best way to stay safe.
- Regularly washing your hands for at least 20 seconds.
- Wearing a face covering in indoor settings where social distancing may be difficult, and where you will come into contact with people you do not normally meet.
- Staying two metres apart from people you do not live with where possible.
- Ensuring work venues are as Covid secure as possible.
- Remembering that if you’ve had your vaccination or previously tested positive for Covid, it’s important that everyone still follows the rules to keep us all safe.
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