The burglary took place at Readings Autos on Freemans Way between 10pm on Tuesday and 6am on Wednesday.
A North Yorkshire Police spokesperson said: "Offenders gained entry to the building and have stolen a large quantity of motor mechanics tools and diagnostic equipment along with two motor bikes – one of which is a Honda CB600F.
"In particular, we are appealing for information about any vehicles seen in the area, which were acting suspiciously or any one selling used tools, specifically SNAP-ON branded items."
Anyone with information that could assist the investigation should contact North Yorkshire Police on 101, select option 2, and ask for James Skaith. You can also email [email protected]
You can also pass on information anonymously to Crimestoppers, on 0800 555 111, quoting North Yorkshire Police reference number 12190059585