John Shires and Gaynor Barnes have been with Yorkshire Television since 1989 and 1991 respectively.
John was once Richard Whiteley's co-anchor and he has covered the Hillsborough stadium disaster as well as big sport stories such as Leeds United's Champions League campaign and the Tour de France Grand Depart.
Gaynor presents the 6pm news programme and some Good Morning Britain bulletins.
John said: "After 32 years at Calendar, it hasn't been an easy decision to retire. I'll miss the people I work with, and I'll also miss the buzz of a live news programme. I can look back on so many stories and momentous events covered, so many friendships made, and so many memories - most of them happy. However, it's time to move on to the next chapter and because I've always tried to keep it a secret, before I go I'll reveal which football club I really support!"
Gaynor added: "Making the decision to leave Calendar hasn't been an easy one. Bringing the news to viewers homes for nearly three decades has been a privilege and a pleasure. My career with the company has certainly surpassed all my expectations. I will, without doubt, miss work and all the wonderful colleagues and friends I've made over the years.
"However, with a rather special birthday looming - I've decided this is now the right time for me to take my gap year."
ITV Calendar's head of news Mark Hayman said: "Their contribution to television in the region has been immense. We know how much our viewers value seeing familiar faces bring them the news each night. John and Gaynor have done that with warmth and authority for many years. We are sad they have decided it's time to leave us, and all of us at ITV News Calendar will miss them, but we wish them both the very best of luck for the future."