Francis Rossi, Rick Parfitt and co will play the city’s flagship venue on Saturday, December 17.
And it promises to be a night to remember for all Quo fans, as the show will form part of the band’s last ever full-on electric tour.
Rossi said: “We’ve talked about it for some time and have decided that it’s time for us to hang up the electrics.
“It’s getting harder and harder for us to play those shows. It’s 30 years since we last said we were stopping but this is a final decision.
“It doesn’t mean we won’t do other things, perhaps the odd special, but we’re agreed that the moment has come.
“There’s more to come from us in the years ahead, but we won’t tour the electric set ever again”.
Parfitt added: “We always thought we’d see a red light when it was time to stop.
“The show hurts now, physically. It’s hard to maintain that level of energy and without that it’s not really a Quo show.
“So we don’t feel we should continue. This is definitely the end of our lives on the road with the electric set, life won’t be the same for us – or many of the fans – but we can’t go on at this pace any more.”
Ticket sales for the show start at 9am this Thursday.
Purchases can be made from the www.firstdirectarena.com website or by calling the box office on 0844 248 1585.