York clinched the Hunters Yorkshire ECB Premier League North title last Saturday to secure their place in the end-of-season competition.
Great Ayton of the North Yorkshire South Durham League will face defending champions Wakefield Thornes in the other semi at Marton.
Both Hanging Heaton and York are competing in the play-offs for the first time and will be battling it out to secure a place in the final at Headingley on Saturday, September 23.
Heaton skipper Gary Fellows said: “The play-off are a great challenge for us.
“Playing at Scarborough is something I always enjoyed with Yorkshire and for many of our team this will be the first time they have played at North Marine Road.
“Winning the title was a big thing for the club and now we would like to go and try and win the play-offs.”
It promises to be a massive final day at the top of Championship One with three sides in with a shout of promotion to the top-flight.
Spice is provided by the fact that leaders Scholes head to second-placed Wrenthorpe, with the gap between the pair being four points.
Seven points adrift of Scholes are third-placed Methley, seeking to do their bit by triumphing at Baildon, in the knowledge that one of the top two is likely to slip up.
Relegation-threatened Yeadon visit rock-bottom Birstall – knowing they will survive if they better Bowling Old Lane’s result.
Hunslet Nelson are in the box seat for the second promotion slot in Championship Two ahead of Altofts.
Nelson welcome Northowram Fields tomorrow and Altotfts welcome Buttershaw St Paul’s.