Following the record-breaking win over Northants Steelbacks, Yorkshire sit in second place in the North division – but five teams below them can still leapfrog them tonight.
Yorkshire need two of Derbyshire, Birmingham, Leicestershire and Northants to lose in their final group games.
With uncertain forecasts for the Midlands, abandonments could prove pivotal to Yorkshire's hopes.
Should any of the four team's matches be wiped out by rain, they will climb above the White Rose in the table.
The Vikings moved above the quartet on Thursday night as their net run rate rose to 1.127 courtesy of Adam Lyth's record innings of 161.
Derbyshire play second bottom Worcestershire and will feel confident of reaching the quarters for a first time since 2005.
Nottinghamshire have already qualified as group winners and Yorkshire will want them to see off Leicestershire.
Off the back of their humiliating defeat at Headingley, reigning champions Northants face bottom of the league Durham where a win would take them up to 16 points and one above Yorkshire.
Lancashire Lightning are the fifth team capable of moving above Yorkshire but they would need to increase their net run rate of 0.240 above the White Rose during a victory against Birmingham.
A narrow Lancashire win would help Yorkshire as it would keep them above the Bears.
Friday night's fixturesDerbyshire Falcons v Worcestershire RoyalsLancashire Lightning v Birmingham BearsNorthants Steelbacks v Durham JetsNotts Outlaws v Leicestershire Foxes.