The club have endured a difficult start to the League One season, losing five of their opening six games.
Brown has paid the price with his job, although it means there is now a vacancy that may prove tempting to out-of-work managers.
Among those currently unemployed are some faces familiar to fans of Yorkshire clubs, and many feature in the list of favourites to succeed Brown.
1. Favourites for Fleetwood Town job
Here are the favourites to become Fleetwood Town's next head coach. Photo: Clive Mason/Getty Images
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