The Minstermen make the long trip to Devon buoyed by last weekend’s comeback win at Hartlepool United, a result that took the Yorkshire club six points clear of the relegation zone.
With no game next weekend due to being knocked out of the FA Cup in the first round, York’s next game after today will be on December 13 at home to AFC Wimbledon, their replay conquerors.
York boss Wilcox said: “We didn’t want a two-week gap, but after Plymouth that is what we have got. It would be great to go in on the back of a decent result.
“Hartlepool was a big win for us, especially as we knew we had Plymouth next and that they have won six (league) games in a row at home, scored 12 goals and conceded none.
“To be able to head to Plymouth with the confidence that a win invariably brings can only be a positive.”
York enjoyed a fruitful end to the emergency loan window as Carlton Morris arrived from Norwich City just before the deadline and a couple of days after Diego De Girolamo’s return from Sheffield United.
Both loanees are in the squad to take on Plymouth along with Josh Carson, who recently returned from an eight-month lay-off caused by a serious knee injury.
Wilcox said: “It has been a good week for us by getting Carlton in along with Diego. They add something at the top end of the pitch and increase our options.
“Josh’s return has also helped a lot and I have noticed a real step up in intensity in training. There is real competition for places now and the players know they have to perform.”