Bolton v Portsmouth
On-loan Vladimir Weiss could start while Andy O'Brien (thigh), Ricardo Gardner (leg) and Chris Basham (knee) are available.
Portsmouth will be without injured trio Nadir Belhadj (hamstring), Jamie O'Hara (back) and Tal Ben Haim (groin).
Man Utd v Tottenham
Wes Brown returns after recovering from a broken foot, but Owen Hargreaves's planned comeback has been delayed by a calf strain. Winger Aaron Lennon could return for Tottenham for the first time in almost four months.
West Ham v Wigan
West Ham will have midfielder Scott Parker back after he completed a two-match suspension. Wigan's Gary Caldwell also returns after serving a three-match ban.
Wolves v Blackburn
Captain Karl Henry completes a three-match ban for his dismissal at Arsenal.
Blackburn will be without Chris Samba (groin) and Brett Emerton (Hamstring).
Aston Villa v Birmingham
Aston Villa are set to be boosted by the availability of Stiliyan Petrov (groin), Richard Dunne (head) and Stephen Warnock (ankle). Birmingham strikers Cameron Jerome (back) and James McFadden (groin) have been passed fit.
Burnley v Liverpool
Burnley defender Clarke Carlisle is doubtful after turning his right ankle in training. Liverpool's David Ngog is a doubt with a back problem.
Chelsea v Stoke
Chelsea will be without suspended John Terry but Stoke's Ryan Shawcross (ankle) returns.
Everton v Fulham
Everton's John Heitinga (ankle) misses out, as does Fulham striker Bobby Zamora. Clint Dempsey could step in.