Zaki, who scored 11 Barclays Premier League goals in a loan spell with Wigan last season, joins the Tigers from Egyptian side Zamalek.
Hull boss Phil Brown will be looking for him to have a similar impact at the KC Stadium as he looks to guide his side out of the drop zone.
A statement on Hull's official website read: "We are pleased to confirm the loan signing of Amr Zaki from Zamalek FC.
"The player yesterday signed a loan agreement until the end of the season to join Hull City AFC.
"As is the case with all non-EU transfers, there are work permit and other red tape issues still to be confirmed, but we are expecting the player to return to England and join Hull City on Friday this week.
"The playing contracts are signed and confirmed, however the final details must be undertaken before the loan can commence."
Hull's leading scorer in the league this season is Stephen Hunt with five.