Blackpool v Fulham
Blackpool defender Ian Evatt is available for the club's first home match after suspension. Fulham could pair Moussa Dembele with Bobby Zamora up front.
Chelsea v Stoke
Brazil midfielder Ramires could make his debut for Chelsea but Branislav Ivanovic (back) is a doubt and Jeffrey Bruma (hernia operation) is out. Stoke striker Kenwyne Jones (ankle) and Liam Lawrence (groin) are hoping to feature.
Man Utd v West Ham
Wayne Rooney (virus) is set to return for United and West Ham are waiting to discover whether they can include new signing Victor Obinna in their squad.
Tottenham v Wigan
Spurs goalkeeper Heurelho Gomes faces a short spell out after injuring his groin and Wigan are without Victor Moses (ankle) for two to three weeks.
Wolves v Newcastle
Wolves' Michael Mancienne, signed for a third loan spell from Chelsea, is likely to be amongst the substitutes. Newcastle bring back the 11 first-team players rested in midweek.
Aston Villa v Everton
Villa striker Gabriel Agbonlahor (calf) is doubtful along with Everton captain Phil Neville (foot).
Bolton v Birmingham (6)
Bolton will assess the fitness of striker Ivan Klasnic (thigh) and Birmingham will check on forward James McFadden.
Liverpool v West Brom
Striker Fernando Torres and captain Steven Gerrard are both set to return for Liverpool. West Brom miss defender Marek Cech (fractured metatarsal).
Sunderland v Man City
Sunderland will be without defender Nedum Onuoha because he is ineligible to face his parent club under the terms of his loan deal. England midfielder James Milner will return to the City squad after sitting out the Europa League victory over Timisoara due to not being registered in time.