The surprise Super League leaders – the only side still with a 100-per-cent win record – look to make it four victories from four outings when Adrian Lam’s side arrive at John Smith’s Stadium.
On whether he expects this to be their toughest examination yet, Woolford said: “I think so.
“Some will say Catalans away round one is a tough test but we handled that okay.
“A lot of people outside this club will look at this game as a bit of a litmus test for us to see where we really are.
“But we can only beat the opposition put in front of us and we’ve performed really well for three weeks in different ways.
“We’ve played in different conditions and got the job done.
“Our defence has held strong and Wigan are a similar team; they’ve had some wins but Adrian Lam will probably openly admit he’ll want them playing a little bit better. Their defence has been great, though so I’m expecting a tight one on Sunday.”
Woolford welcomes back Jordan Turner and hopes James Gavet and Darnell McIntosh will be fit to resume after suffering injuries at Hull KR.
Huddersfield’s postponed game against Leeds Rhinos has been rescheduled for Tuesday April 28 (7.45pm).
To facilitate that, Giants’ home matches with Salford Red Devils and Warrington Wolves have subsequently been moved to Thursday April 23 (7.45pm) and Saturday April 18 (3pm).
Similarly, Leeds’s home game with Salford has been shifted back to Sunday May 3 (7.45pm).
Elsewhere, Toronto Wolfpack have signed young Wigan forwards Ben Kilner and Jack Wells on one-month loan deals and they come straight into the squad against St Helens.
Tributes have been paid to former Hull FC forward Adam Maher who has died aged 47.
The Australian, who played 100 times for FC, had motor neurone disease since late 2018.