Doncaster’s reward for a 35-28 win over North Wales Crusaders is a home tie against London Skolars.
York City Knights - who beat Yorkshire rivals Hunslet Hawks 24-4 yesterday - are the road at Rochdale Hornets.
Keighley Cougars play host to Oxford, after beating Wath Brow Hornets 10-4 on Saturday
Doncaster actually trailed 22-18 against Crusaders, but tries from Matty Welham, Jordan Abdull (2), Jordie Hedges (2) - who also kicked three goals and a drop goal - Kieran Cross and David Foggin-Johnston secured safe passage.
Tries from Nev Morrison, Brett Turner, Russ Spiers, Richard Wilkinson - plus four Danny Nicklas goals - gave York a 24-4 win over Hunslet, who replied with a Richie Barnett try.
The 2016 iPro Sport Cup 2nd round draw: Doncaster v London Skolars, Keighley Cougars v Oxford, Rochdale Hornets v York City Knights, University of Gloucestershire All Golds v Newcastle Thunder. Ties to be played over weekend of April 2-3.