Sheffield Wednesday v Bristol Rovers: Operation blow for rising Owls star Coke
The 24-year-old has been a regular for the Owls this season despite being troubled by the injury in recent weeks.
Manager Irvine said: "Giles is having an exploratory operation so we can find out exactly what the problem is.
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Hide Ad"His knee has been troubling him for a few weeks and, hopefully, we can get to the bottom of it. It is a blow for Giles because he has had an excellent start to his career at Sheffield Wednesday.
"He has played well, scored some goals and looked a very good player."
Coke, who has been involved in all but four of Wednesday's 19 league outings, moved to Hillsborough last summer on a free transfer from Motherwell and has since netted four goals.
Irvine said: "As I have said from the start of the season, we have a good squad but not a big squad."