Alice Barber and Clementine Vann-Alexander first met one another at the age of 11, when they were pupils at Harrogate Ladies College.
Their shared love of theatre and performance has led them, ten years later, to form new theatre company Prohibition Theatre.
The History Boys will be their very first production and has been granted permission by Alan Bennett himself.
Alice, who is a student at Durham University, said: “There’s been a lot of debate over a lack of depth in many female roles in the theatre.
"This play is all about boys, so to cast women to play them brings an entirely new dynamic.”
Clementine, who is a student at Bristol University, said: “When I graduate I’m hoping to become an actor and director, and Alice is hoping to go into theatre production. We’re passionate about this production, and we have a fantastically talented cast on board. We cannot thank Alan Bennett enough for his help at the start of our careers.”
The show will be performed on Saturday, June 18 at North Road Methodist Church in Durham.
The all-female cast of The History Boys
Crowther: Angharad Davies
Dakin: Abbie Cole
Irwin: Charlie Whitehead
Hector: Poppy Kelham
Timms: Christie Clark
Totty: Francesca Sollohub
Scripps: Lara Janes-Walton
Lockwood: Lucy Booth
Posner: Louisa Quarterman
Akthar: Cassandra Bailey
Rudge: Saroj Spickett
Headmaster: Clementine Vann-Alexander
Director: Clementine Vann-Alexander
Producer: Alice Barber