The fire broke out at a property in Washer Lane about 1.15pm on Friday, April 23.
Six fire engines are currently at the scene.
There are also two aerial ladder platforms, one each from Bradford and Leeds fire stations.
Residents have been warned to keep doors and windows closed.
A West Yorkshire Fire & Rescue Service spokeswoman said: "We are currently in attendance at a fire in a building off Washer Lane in Halifax.
"Our control room received a call at 1.16pm.
"There are currently six fire engines on the scene from across the Service plus two aerial ladder platforms, one each from Bradford and Leeds fire stations.
"Residents in the area are advised to keep doors and windows closed."
In an update issued at 4pm, the fire service said: "Crews are now damping down and we’re able to scale back our resources – there will shortly be two fire engines left at the scene.
"Crews will likely be on scene for some time damping down.
"Thanks to local residents for their patience while we dealt with the fire, and also to our partners at Calderdale Council and West Yorkshire Police for their work during the incident."