O’Brien’s three-year-olds currently share 12-1 favouritism with compatriot Quick Jack, trained by Tony Martin, and the Roger Charlton-trained Quest For More.
Dermot Weld, Ger Lyons, Gordon Elliott and Willie Mullins also have entries in a 115-horse list for Europe’s richest Flat handicap.
Pallasator, fourth as the 9-2 favourite in the race last season, might try again for Sir Mark Prescott, while others of note include Arab Dawn (Hughie Morrison) and Ajman Bridge (Luca Cumani).
York’s Group Two Pinsent Masons Lowther Stakes on August 20 has lured 45 fillies, including runaway Royal Ascot scorer Acapulco, who is also engaged in the Coolmore Nunthorpe Stakes a day later.
Easton Angel, runner-up to Wesley Ward’s American ace in the Queen Mary, could renew rivalry for the Michael Dods operation.