Aston Villa 1 Sheffield Wednesday 2: Fletcher nets Owls winner
Jordan Thorniley missed out with a calf injury sustained in the midweek defeat at Nottingham Forest, meaning defensive recalls for Michael Hector and Daniel Pudil.
The Owls went in front on 49 minutes, Portuguese forward Marco Matias on target.
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Hide AdBut the lead lasted just four minutes, before John McGinn smashed in an equaliser for the hosts.
Steven Fletcher netted his second goal in four days - after scoring against Forest on Wednesday night - to nudge the Owls back in front on 67 minutes.