Barnsley will travel to Bramall Lane this weekend off the back of a brilliant win over Bristol City midweek.
The Tykes have now suffered only one defeat in six matches and will be confident of causing an upset against promotion-chasing Sheffield United.
The Blades currently sit nineth in the Championship, only one point off the top six.
A win for Barnsley could see them move out of the bottom three - with it looking increasingly likely that it will be between themselves and Reading as to who finishes in the relegation zone alongside Derby County and Peterborough United.
The Royals face a tough test against Blackburn Rovers this weekend, before Barnsley host them in a huge six pointer in the following match.
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The Blades currently sit nineth in the Championship, only one point off the top six.