A number of sides will be hoping to seal a play-off place while the top two, Wigan Athletic and Rotherham United, will be aiming to stay ahead of the chasing pack and secure promotion to the Championship.
There have been a number of fine individual performers in the Rotherham side this season, with four Millers players making the cut in our best XI of the campaign.
One Sheffield Wednesday man is named while players from Wycombe Wanderers, Sunderland, MK Dons, Oxford United and Accrington Stanley are also included.
With the majority of sides having to play six or more games before the end of the campaign, the team could look different come the end of April.
For outfield players, only those who have played in 30 or more games have been considered for selection.
So, here is our League One Team of the Season so far in a 3-4-1-2 formation, see if you agree...
1. GK - Josh Vickers
The Rotherham United goalkeeper has kept 12 clean sheets in 20 appearances and conceded just 11 goals, since becoming a regular in Paul Warne's side. Photo: Getty Images
2. CB - Ross Sykes
The Accrington Stanley centre-back has enjoyed an impressive season and even chipped in with contributions up front, scoring three goals and providing four assists. Photo: Getty Images
3. CB - Joe Jacobson
The centre-back has missed just five games this season. Along with some strong defensive displays, he has also claimed three goals and three assists, with Wycombe just outside the play-off places. Photo: Getty Images
4. CB - Michael Ihiekwe
The Rotherham defender has been involved in the majority of the Millers' games and is recognised as one of the division's best centre-backs. He also has four goal contributions, with two goals and two assists. Photo: PA Wire