The clubs are level on points in the Premier League, sat on 26 points in 16th and 17th respectively. With 18th-placed West Ham United showing signs of life, the need for Leeds and Forest to pick up points is strong.
Leeds, for the most part, have been a different beast since early December. They have switched to a flexible 3-5-2 system and looked more comfortable as a result.
However, the Whites were issued a stern reminder of how tough the Premier League can be as they were dismantled by Arsenal last week.
Forest, meanwhile, shared the spoils with Crystal Palace in a 1-1 draw despite going down to 10 men.
Speaking in his pre-match press conference, Leeds boss Daniel Farke said: "Sean [Dyche] has a proven record at Premier League level. He gave lots of stability on Premier League level.
“His team has lots of quality and qualified for Europe last season. They very often have clean sheets or have conceded just one goal. I expect a tight game where it will be difficult to create chances so we have to be on it. We will need our supporters."
Ahead of the mouthwatering meeting between Leeds and Forest in LS11, here is a round-up of the team news across both camps.
9. Daniel James - doubt
After a lengthy spell on the sidelines, the jet-heeled winger could be back in the squad. Farke said James was "making progress". | George Wood/Getty Images
10. Chris Wood - out
The New Zealand international is still out with a knee problem and will not face his former club. | Nick Potts/PA Wire
11. Lukas Nmecha - doubt
Farke has said it is "probably unlikely" the Germany-capped forward will be back from injury. The Leeds boss said: "Lukas Nmecha is not in team training yet. We have two more days. It's probably unlikely that he will make it for this game. But he's also not too far away. We'll see." | Mike Egerton/PA Wire
12. Nicolo Savona - out
The young defender has been struggling with a knee injury and is expected to be absent again. | Mike Egerton/PA Wire