The Spaniard was recruited in 2017, having previously overseen transfer dealings at Middlesbrough. He brought gems such as Raphinha and Wilfried Gnonto to Elland Road, but there were also some considerably less successful signings made on his watch.
Following the official confirmation of his exit, The Yorkshire Post has explored his biggest hits and misses in the transfer market.
. Jean-Kevin Augustin - miss
The forward managed just 48 minutes for Leeds and the club were recently ordered to pay £24.5m after being found to have breached his contract. Photo: Bruce Rollinson
. Raphinha - hit
The Brazilian winger lit up Elland Road with his flair and was a firm favourite among supporters. Photo: Tony Johnson
. Kiko Casilla - miss
The goalkeeper was considered a coup when he arrived at the club from Real Madrid in 2019. However, he failed to replicate the form he had shown to earn his Spain debut in 2014. Photo: Tony Johnson
. Ezgjan Alioski - hit
Charismatic, versatile and hardworking - the North Macedonia international ticked plenty of boxes. Photo: Bruce Rollinson
. Izzy Brown - miss
The playmaker managed just one solitary appearance for the club. By the time he stepped on the pitch against Derby County in the second leg of the 2019 play-off semi-final, Leeds' dreams of promotions were already fading. Photo: Tony Johnson
. Mateusz Klich - hit
The Polish midfielder won plaudits for his all-action displays and was instrumental in the promotion-winning 2019/20 campaign. Photo: Bruce Rollinson
. Laurens De Bock - miss
Left-back has proven to be a troublesome position at Elland Road and De Bock struggled after joining from Club Brugge in 2018. Photo: Tony Johnson
1. Jean-Kevin Augustin - miss
The forward managed just 48 minutes for Leeds and the club were recently ordered to pay £24.5m after being found to have breached his contract. Photo: Bruce Rollinson
2. Raphinha - hit
The Brazilian winger lit up Elland Road with his flair and was a firm favourite among supporters. Photo: Tony Johnson
3. Kiko Casilla - miss
The goalkeeper was considered a coup when he arrived at the club from Real Madrid in 2019. However, he failed to replicate the form he had shown to earn his Spain debut in 2014. Photo: Tony Johnson
4. Ezgjan Alioski - hit
Charismatic, versatile and hardworking - the North Macedonia international ticked plenty of boxes. Photo: Bruce Rollinson