The Millers return to action in Tuesday night's match with the Hornets at the AESSEAL New York Stadium after a number of positive cases of Covid-19 among players and staff forced the club to postpone their recent games against Brenford, Luton and Coventry - with the virus having spread through the camp.
With individuals having self-isolated in line with Government advice, the situation has cleared up sufficiently to allow the club to re-open their Roundwood training ground and prepare and get ready for the club's next two matches before the international break.
Warne also spent a spell in self-isolation in October after one of his family members tested positive for coronavirus - missing the games with Norwich City and Nottingham Forest.
He will now oversee the club's next two matches remotely, with first team coach Matt Hamshaw also self-isolating for tomorrow's home game with the Hornets.
Assistant manager Richie Barker and goalkeeping coach Andy Warrington will take charge in the dug-out in midweek.
Warne said: "We have been hit really, really hard this time. It has gone through the camp and we've had a significant number of people self-isolating, including myself now.
"The lads’ first day back in will be today, as I do this interview on Monday.
"They won't have myself, Richie or Hammy there, but fortunately we've got Andy Warrington to oversee training.
"Richie will be able to take a session with the lads on Tuesday morning to take them through some work to prepare them as well as we can technically.
"I'll be watching from afar - although I'm not sure whether I'll be able to listen to Breck's (John Breckin) commentary going through all of the emotions of it!”
The Millers, who have a number of games in hand on their rivals, have not played since March 3.